Buah Merah and People Behind

by Mathelda Kurniaty Roreng, S.TP, M.Si
and Toshiaki Nishigaki, Ph.D


Health Benefits of Buah Merah Oil

Health benefits of provitamin A carotenoids are also well summarized by the Linus Pauling Institute, Oregon State University in USA (12) . 

It is well-known that high doses of beta-carotene (considered as synthetic substance, 20~30 mg/day) supplementation to smokers and/or workers with a history of occupational asbestos exposure increased the risk of lung cancers.

In contrast, there are many reports that dietary intake of beta-cryptoxanthin was inversely associated with significant reductions in risk of lung cancer in cohort clinical studies.

Experimental animal studies demonstrated that beta-cryptoxanthin had anti-cancer effects in the large intestines and lungs, and prevented osteoporosis and improved diabetes mellitus (16~19).

With regards to Buah Merah oil, there are various empirical reports of improvement for stamina, hypertension, gout, allergy, eczema, cancers, hepatitis, AIDS/HIVs, hair-growth, constipation, lower body temperature and so on, but the effects of Buah Merah oil have not been completely established (5, 6, 13, 20~22).

In Japan, it has been reported that Buah Merah oil inhibited proliferation of cancer cells such as S-180, Lewis lung cancer, human non-small lung cancer A549 and human gastric cancer K-MK-6 cell lines in mice (23, 24). When Buah Merah oil was given to SHR-SP rats, it increased in longevity of SHR-SP rats by 20 % (25). 

In vitro studies using melanoma cell B16 line revealed that Buah Merah oil was not cyto-toxic until the concentrations of 400 μg/mL and suppressed melanogenesis and tyrosinase activity in a dose-dependent manner (26). 

It is suggested from an additional study that suppression of melanogenesis is probably associated with stimulated degradation of tyrosinase through ubiquitin-proteasome system (27).

Beta-cryptoxanthin suppresses the growth of human non-small-cell lung cancer cells, A549 cells in vitro by approximate 50% at concentration of 20 μmol/L (28). 

In contrast, 500 μg/mL (equivalent to 0.05 μmol/L of beta-cryptoxanthin) of Buah Merah oil suppresses the growth of A549 cancer cells by 97.5% (23). 

These findings indicate that Buah Merah oil has more than 400-fold stronger action in suppression of A4549 cell growth as long as beta-cryptoxanthin levels are concerned.

We speculate that Buah Merah oil may exert suppression of cancer cell growth not only by beta-cryptoxanthin’s action but also by synergistic effects with unknown ingredients, probably other carotenoids.

Recently, it was found from preliminary clinical studies that ingestion of Buah Merah capsules revealed growth of hairs, improved acne and prohibited hair loss.
Thus, Buah Merah capsule products are expected as novel nutra-cosmetic agent by taking them orallly.

Buah Merah products are categorized as traditional herbal medicine in Indonesia. 
Indonesian Buah Merah products claim the benefits or efficacy for cancers, stroke and hypertension, gout, diabetes mellitus, oesteoporosis, eye disorders, improvement of intelligence and infertile.

On the other hand, Buah Merah products are classified as dietary food in Japan and Korea, therefore they are claimed for use of dietary food to intake natural micronutrients and fruit oil.


Conclusion

Buah Merah is Papua-originated rare and unique plant and fruit that has been providing functional and essential micronutorients such as provitamin A carotenoids and vitamin E as well as fruit flesh oil to Papuan native folks living at highland areas under poor environments for more than 30,000 years.

Buah Merah is likely to provide various actions for human health in related to rich contents of provitamin A carotenoids, especially beta-cryptoxanthin. Beta-cryptoxanthin may exert synergic actions with other carotenoids or unknown ingredients.

The long history and experiences of use of Buah Merah by Papuan people proves the strong evidence of safety. 

There are no adverse events reported in Indonesia, Japan and the other countries in human use. In addition, the toxicity studies of Buah Merah oil do not reveal any toxic findings caused by Buah Merah oil.

There is no reason to limit consumption of Buah Merah oil because Buah Merah oil is pure dietary food derived from Buah Merah fruit. However, daily acceptable highest dose of Buah Merah oil may be 10 g/day from dietary custom of native Papuan people.



Dr. Nishigaki Toshiaki, is a Japanese doctor who first discovered the presence of beta-cryptoxanthin in Buah Merah.

He distributes pure Buah Merah oil capsules as well. See photo below;

Buah Merah 500VE is good for fanatic smokers, patients with cancers, DM, post-menopausal oesteoporosis, acne, boldness, malnutrition and other serious diseases, and for enhance of your health, longevity.

Buah Merah trees are naturally grown and specifically cultivated in the highland areas of Papua as described above.

They seem likely to be originated in Papua and to be rare and unique plant species. 

Therefore, Buah Merah is forbidden to bring it out of Indonesia and to get any patent without permission of Indonesia Government.

In 2007, Center for Agro-Based Industry, Ministry of Industry, Indonesian Government and M&K Laboratories Inc.Japan entered into Material Transfer Agreement (MTA) based on biodiversity treaty of the United Nations, 2003. 

In addition, Buah Merah is subject to collaborate in research and development following Memorandum of Understanding (MOU) with both parties.

Material Transfer Agreement (MTA) and MOU were made between Indonesian Government and M&K Laboratories Inc. in 2007

PHOTOS: February 2016 meeting with Essensa owners and Dr. Nishigaki. Mam Joy Alcasabas has the exclusivity for high grade Buah Merah oil distribution in the Philippines


Essensa Naturale is the exclusive distributor of Buah Merah 500VE and the raw oil from Nishigaki

Ma'am Joy Alcasabas through her company provides Abaca fibers to Japan, which are used as raw materials in making Japanese bills. 

Nishigaki is her contact for this deal. 

Nishigaki shared the info about Buah Merah with Ma'am Joy. 

Later on Ma'am Joy formulated a much cheaper alternative since the pure Buah Merah Oil is quite expensive.

She mixed it with known anti-cancer fruits and super foods. The new product was named as Buah Merah Mix. The 6 contents were;

1. Guyabano
2. Mangosteen  
3. Buah Merah
4. Moringa
5. Barley
6. Wheat Grass

The result was a big surprise! The mix provided a synergistic effect. 

Many have recovered from serious illnesses such as cancer, diabetes, hypertension, asthma and other diseases. An HIV patient even survived because of Buah Merah Mix. His retroviral drug was not enough. Only when he started taking Buah Merah Mix did his health status improved. 

Many who suffered from Breast Cancer have miraculously got healed.

Buah Merah Mix is now the country's best-selling herbal juice.

TO ENSURE GETTING HIGH-QUALITY BUAH MERAH, CHOOSE ESSENSA

Only Dr. Nishigaki Toshiaki has been granted the permit to import high-grade Buah Merah from Indonesia.

Material Transfer Agreement (MTA) and MOU were made between Indonesian Government and M&K Laboratories Inc. in 2007

There are around 30 varieties of Red Fruit, but only four variants have high economy values: merah panjang (long red), merah pandek (short red), cokelot (brown), and kummiming (yellow). The Red Fruit variant used as medicine is merah panjang (long red). The size is around 100 cm in length, 18 cm in diameter length, and 7.5 kg in weight. The fruit has a blunt edge and cylindrical shape.

In the Philippines, only Essensa Naturale via Ma'am Joy Alcasabas is the exclusive distributor of the BUAH MERAH 500VE and the raw oil, which is used in making BUAH MERAH MIX.

Those who claim they also have Buah Merah might have sourced the Buah Merah from other suppliers who can only provide low-quality oil.

Worse, they can only claim but in reality, there's no Buah Merah oil.

To get authentic products with authentic high-grade Buah Merah oil, choose Essensa.